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Castleman Disease of the Hyaline-Vascular Type Confined to the Kidney

Nicole A. Mah, Samuel J. Peretsman MD, Chris M. Teigland MD, Peter M. Banks MD
DOI: http://dx.doi.org/10.1309/51U9EWBTPQAM61TT 465-468 First published online: 1 March 2007

Abstract

The case is a 38-year-old man in whom a solitary subcapsular left renal cortical mass was successfully resected. Comorbidities included a benign epididymal cyst and a history of nephrolithiasis. Computed tomographic imaging demonstrated a 1.8-cm enhancing mass in the anterior midregion of the kidney. An open partial nephrectomy was performed, and histopathologic examination established a diagnosis of the hyaline-vascular type of Castleman disease (CD). The patient had an uneventful postoperative course and has experienced no local or metastatic recurrence in the 10 months since surgery. CD localized in the kidney is an exceptionally rare occurrence but should be included in the complete differential diagnosis of solitary renal cortical mass lesions.

Key Words:
  • Castleman disease
  • Kidney
  • Angiofollicular lymph node hyperplasia
  • Renal cortex
  • Giant lymph node hyperplasia