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Pathologic Features of Chronic Hepatitis
A Review and Update

Kamal G. Ishak MD, PhD
DOI: http://dx.doi.org/10.1309/42D6-W7PL-FX0A-LBXF 40-55 First published online: 1 January 2000


The general histopathologic changes of chronic hepatitis and those related to the various causes are reviewed. Consideration also is given to underlying or associated diseases and to mixed infections in chronic viral hepatitis. Changes occurring in exacerbations or relapses are described. Selected histopathologic changes are illustrated. The nomenclature is reviewed briefly, with emphasis on separation of activity from stage of disease.

Key Words:
  • Chronic hepatitis C
  • Chronic hepatitis B
  • Autoimmune hepatitis
  • Pathology
  • Nomenclature